Ensure all your SKSE plugins are updated for 1.6.640.
From now on, always launch your game using skse64_loader.exe . You can create a desktop shortcut for convenience.
Go to Vortex's Dashboard, click the three-dot menu next to the SKSE tool, select Edit , and verify that the "Target" and "Start In" fields both point to your correct Skyrim installation folder (the same folder containing skse64_loader.exe ). skse 16640 link
Right-click Skyrim Special Edition -> Manage -> Browse local files.
GOG uses a slightly different executable. GOG’s version 1.6.640 requires a (also on silverlock.org under "GOG SE build"). Ensure all your SKSE plugins are updated for 1
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For anyone modding on the 1.6.640 runtime, SKSE 2.2.3 is an absolute necessity. It expands the Papyrus scripting language, allowing for advanced features like the SkyUI MCM (Mod Configuration Menu) , complex combat overhauls, and dynamic engine fixes. Go to Vortex's Dashboard, click the three-dot menu
Are you planning to your game from the latest version to 1.6.640, or are you setting up a new mod list from scratch?
If the above direct link does not work, visit the official SKSE page and look for the "Current Anniversary Edition build 2.2.1 (game version 1.6.640)" link. 3. Installation Guide (Step-by-Step)
To run mods on Skyrim version 1.6.640, you specifically need . Using a newer version (like 2.2.6+) or an older one will result in a version mismatch error when you try to launch the game.
Once SKSE is installed, you can no longer launch Skyrim through Steam or the default Steam desktop shortcut if you want to play with SKSE-dependent mods.